Inflammation - friend or enemy?

• Musa R. Khaitov
• Andrey P. Prodeus
• Ivan G. Kozlov

Abstract

Inflammation and its role in the pathogenesis of numerous diseases is the subject of research and the field for discussions at International and Russian scientific and medical events with the participation of physicians of different specialties. This topic was also discussed at the interdisciplinary panel discussion «Inflammation - friend or enemy?» with the participation of leading experts in the field of immunology, allergology and clinical pharmacology, held within the framework of the 17^th International Interdisciplinary Congress on Allergology and Immunology (Moscow, June 23-25, 2021). The interrelation of allergy and the expressed inflammatory process as a result of the action of immune mechanisms underlying allergic diseases in recent years requires increasing attention of the medical community due to the steady increase of the prevalence of allergic diseases. A significant place in the treatment of such diseases still have glucocorticosteroids, the discovery of the structure and biological effects of which was awarded by Nobel Prize in 1950. A wide range of physiological and pharmacological effects of glucocorticoids, in particular, antiinflammatory, nonspecific membrane stabilizing and decongestance, antiallergic and immunosuppressive, antishock, etc., makes these compounds almost universal drugs that are indicated for many pathological conditions at different stages of their development. Special attention during the discussion was paid to the Diprometa® preparation, betamethasone in a convenient pre-filled syringe, which makes its use relevant for a wide range of diseases and conditions.

Keywords:inflammation; allergic diseases; insect allergy; anaphylactoid reactions; rheumatic diseases; COVID-19; glucocorticosteroids; betamethasone sodium phosphate; betamethasone dipropionate

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