Doubts and hopes of allergology
Abstract
The main aspects of the development of an allergic reaction, evolutionary stages of allergy formation, effector cells and regulatory molecules involved in an allergic reaction are reviewed in the article. The biological role of allergy is discussed. The need for an in-depth study of the mechanisms of allergic processes is noted, which is the basis for the development of highly effective allergy control drugs and the creation of improved algorithms for allergen-specific immunotherapy.
Keywords:allergy; anaphylaxis; monoclonal antibodies; IgE; effector cells; cytokines; mast cells; eosinophils
For citation: Gushchin I.S. Doubts and hopes of allergology. Immunologiya. 2023; 44 (4): 471–80. DOI: https://doi.org/10.33029/0206-4952-2023-44-4-471-480 (in Russian)
Funding. The study had no sponsor support.
Conflict of interests. The author declares no conflict of interests.
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